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arc1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540002, updated on 11-Sep-2024

Summary

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Official Symbol
arc1
Primary source
PomBase:SPBC14C8.06
Locus tag
SPOM_SPBC14C8.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
sop2
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Genomic context

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Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (2214398..2215817)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene acetolactate synthase regulatory subunit Ilv6 Neighboring gene ncRNA Neighboring gene glucan-alpha-1,4-glucosidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MCM loader

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments. Espinoza-Sanchez S, et al. Proc Natl Acad Sci U S A, 2018 Sep 11. PMID 30150414, Free PMC Article
  2. A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Morrell JL, et al. Mol Biol Cell, 1999 Dec. PMID 10588653, Free PMC Article
  3. Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function. Balasubramanian MK, et al. EMBO J, 1996 Dec 2. PMID 8978670, Free PMC Article
  4. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
  5. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding EXP
Inferred from Experiment
more info
 PubMed 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin filament binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Arp2/3 complex-mediated actin nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in actin cortical patch assembly IC
Inferred by Curator
more info
  
involved_in actin filament branching EXP
Inferred from Experiment
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endocytosis IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
part_of Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Arp2/3 protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cortical patch IC
Inferred by Curator
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
ARP2/3 actin-organizing complex WD repeat subunit Sop2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2214398..2215817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021817.3 → NP_595909.1  ARP2/3 actin-organizing complex WD repeat subunit Sop2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595909.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O60088, P78774
    Conserved Domains (2) summary
    sd00039
    Location:17 → 53
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:49 → 231
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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