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suc1 cyclin-dependent protein kinase regulatory subunit Suc1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540027, updated on 18-Sep-2024

Summary

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Official Symbol
suc1
Official Full Name
cyclin-dependent protein kinase regulatory subunit Suc1
Primary source
PomBase:SPBC1734.14c
Locus tag
SPOM_SPBC1734.14C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
p13
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Genomic context

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See suc1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (1087538..1088832, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F1-ATPase gamma subunit atp3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RSC complex bromodomain subunit Rsc4 Neighboring gene SIN3 family co-repressor, Clr6 and Rpd3L histone deacetylase complex subunit Pst3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Domain swapping in p13suc1 results in formation of native-like, cytotoxic aggregates. Rousseau F, et al. J Mol Biol, 2006 Oct 20. PMID 16963085
  2. Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. Bourne Y, et al. Proc Natl Acad Sci U S A, 1995 Oct 24. PMID 7479758, Free PMC Article
  3. The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein. Endicott JA, et al. EMBO J, 1995 Mar 1. PMID 7889931, Free PMC Article
  4. Structural role of the proline residues of the beta-hinge region of p13suc1 as revealed by site-directed mutagenesis and fluorescence studies. Simeoni F, et al. Biochemistry, 2001 Jul 10. PMID 11434772
  5. Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer. Khazanovich N, et al. Structure, 1996 Mar 15. PMID 8805536

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cyclin-dependent protein serine/threonine kinase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signaling NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cyclin-dependent protein kinase holoenzyme complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
cyclin-dependent protein kinase regulatory subunit Suc1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1087538..1088832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021339.3 → NP_595431.1  cyclin-dependent protein kinase regulatory subunit Suc1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595431.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P08463
    Conserved Domains (1) summary
    pfam01111
    Location:27 → 101
    CKS; Cyclin-dependent kinase regulatory subunit
Nucleotide Protein
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