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exo70 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540127, updated on 22-Aug-2024

Summary

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Official Symbol
exo70
Primary source
PomBase:SPBC106.20
Locus tag
SPOM_SPBC106.20
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
exo7; SPBC582.02
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Genomic context

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See exo70 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003423.3 (417243..419867)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Ppr10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G2/M B-type cyclin Cdc13 Neighboring gene ncRNA Neighboring gene protein dsh1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast Sec3 and Exo70 are transported on actin cables and localize the exocyst complex to cell poles. Bendezú FO, et al. PLoS One, 2012. PMID 22768263, Free PMC Article
  2. Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex. Tay YD, et al. Cell Rep, 2019 Feb 5. PMID 30726745, Free PMC Article
  3. Rho3p regulates cell separation by modulating exocyst function in Schizosaccharomyces pombe. Wang H, et al. Genetics, 2003 Aug. PMID 12930742, Free PMC Article
  4. Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton. Jourdain I, et al. Traffic, 2012 Nov. PMID 22891673, Free PMC Article
  5. The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe. Wang H, et al. Mol Biol Cell, 2002 Feb. PMID 11854409, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Orb6 phosphorylation of Sec3 contributes to exocyst function in concert with exocyst protein Exo70.
    Title: Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in intracellular protein transport IC
Inferred by Curator
more info
 PubMed 
involved_in vesicle tethering involved in exocytosis IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exocyst IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
exocyst complex subunit Exo70

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    417243..419867
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021078.3 → NP_595170.2  exocyst complex subunit Exo70 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595170.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10339
    Conserved Domains (1) summary
    pfam03081
    Location:253 → 609
    Exo70; Exo70 exocyst complex subunit
Nucleotide Protein
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