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mti2 translation initiation factor IF-2Mt [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540181, updated on 18-Sep-2024

Summary

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Official Symbol
mti2
Official Full Name
translation initiation factor IF-2Mt
Primary source
PomBase:SPBC1271.15c
Locus tag
SPOM_SPBC1271.15C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mti2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (334066..336676)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutamate N-acetyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe Mti2 and Mti3 act in conjunction during mitochondrial translation initiation. Luo Y, et al. FEBS J, 2019 Nov. PMID 31350787
  2. The Schizosaccharomyces pombe PPR protein Ppr10 associates with a novel protein Mpa1 and acts as a mitochondrial translational activator. Wang Y, et al. Nucleic Acids Res, 2017 Apr 7. PMID 28334955, Free PMC Article
  3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity ISO
Inferred from Sequence Orthology
more info
  
enables RNA binding ISO
Inferred from Sequence Orthology
more info
  
enables mitochondrial ribosome binding EXP
Inferred from Experiment
more info
 PubMed 
enables translation initiation factor activity EXP
Inferred from Experiment
more info
 PubMed 
enables translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translational initiation EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitochondrial translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
translation initiation factor IF-2Mt

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    334066..336676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021043.3 → NP_595135.1  translation initiation factor IF-2Mt [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595135.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O59683
    Conserved Domains (6) summary
    cd01887
    Location:172 → 337
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    COG0532
    Location:169 → 686
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    pfam04760
    Location:96 → 143
    IF2_N; Translation initiation factor IF-2, N-terminal region
    pfam11987
    Location:474 → 572
    IF-2; Translation-initiation factor 2
    cd03692
    Location:590 → 676
    mtIF2_IVc; C2 subdomain of domain IV in mitochondrial translation initiation factor 2
    cd03702
    Location:346 → 442
    IF2_mtIF2_II; Domain II of bacterial and mitochondrial Initiation Factor 2
Nucleotide Protein
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