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rrp43 exosome subunit Rrp43 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540189, updated on 18-Sep-2024

Summary

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Official Symbol
rrp43
Official Full Name
exosome subunit Rrp43
Primary source
PomBase:SPBC17D1.03c
Locus tag
SPOM_SPBC17D1.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rrp43 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (3331682..3332945, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene transcriptional regulatory protein Spp41 Neighboring gene ncRNA Neighboring gene diphthamide biosynthesis protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase I upstream activation factor complex subunit Acr1 Neighboring gene protein rhs1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex. Weick EM, et al. Cell, 2018 Jun 14. PMID 29906447, Free PMC Article
  2. The Sm complex is required for the processing of non-coding RNAs by the exosome. Coy S, et al. PLoS One, 2013. PMID 23755256, Free PMC Article
  3. The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway. Malecki M, et al. EMBO J, 2013 Jul 3. PMID 23503588, Free PMC Article
  4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  5. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity ISO
Inferred from Sequence Orthology
more info
  
enables mRNA 3'-UTR AU-rich region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in TRAMP-dependent tRNA surveillance pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in U1 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in U4 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in U5 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nonfunctional rRNA decay ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear mRNA surveillance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear polyadenylation-dependent mRNA catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear polyadenylation-dependent rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear-transcribed mRNA catabolic process, non-stop decay ISO
Inferred from Sequence Orthology
more info
  
involved_in rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of cytoplasmic exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
part_of exosome (RNase complex) IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear exosome (RNase complex) EXP
Inferred from Experiment
more info
 PubMed 
part_of nuclear exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
exosome subunit Rrp43

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3331682..3332945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022306.3 → NP_596385.1  exosome subunit Rrp43 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596385.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10205
    Conserved Domains (2) summary
    cd11369
    Location:18 → 269
    RNase_PH_RRP43; RRP43 subunit of eukaryotic exosome
    COG2123
    Location:12 → 270
    Rrp42; Exosome complex RNA-binding protein Rrp42, RNase PH superfamily [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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