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rrn7 RNA polymerase I general transcription initiation factor subunit Rrn7 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540236, updated on 17-Aug-2024

Summary

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Gene symbol
rrn7
Gene description
RNA polymerase I general transcription initiation factor subunit Rrn7
Primary source
PomBase:SPBC336.09c
Locus tag
SPOM_SPBC336.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rrn7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (2756276..2758283, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene transcription factor TFIIIC subunit Sfc3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Spc24 Neighboring gene putative translation elongation factor eIF5A Neighboring gene GARP complex subunit Vps52 Neighboring gene DNA-binding transcription factor, MBF transcription factor complex subunit Cdc10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rrn7 protein, an RNA polymerase I transcription factor, is required for RNA polymerase II-dependent transcription directed by core promoters with a HomolD box sequence. Rojas DA, et al. J Biol Chem, 2011 Jul 29. PMID 21673110, Free PMC Article
  2. Characterization of a fission yeast subunit of an RNA polymerase I essential transcription initiation factor, SpRrn7h/TAF(I)68, that bridges yeast and mammals: association with SpRrn11h and the core ribosomal RNA gene promoter. Boukhgalter B, et al. Gene, 2002 May 29. PMID 12095692
  3. Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe. Moreira-Ramos S, et al. FEBS J, 2015 Feb. PMID 25410910
  4. RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe. Montes M, et al. FEBS J, 2017 Feb. PMID 28060464
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression.
    Title: RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe.
  2. data suggest that CK2 inhibits ribosomal protein gene transcription in S. pombe via phosphorylation of Rrn7 at Thr67.
    Title: Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe.
  3. Rrn7 is an excellent candidate to be involved in the coordination of ribosomal DNA and ribosomal gene transcription during ribosome synthesis.
    Title: Rrn7 protein, an RNA polymerase I transcription factor, is required for RNA polymerase II-dependent transcription directed by core promoters with a HomolD box sequence.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA polymerase I core promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase I core promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to RNA polymerase I general transcription initiation factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA polymerase I preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation at RNA polymerase I promoter IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I core factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase I transcription regulator complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
RNA polymerase I general transcription initiation factor subunit Rrn7

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2756276..2758283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022047.3 → NP_596129.1  RNA polymerase I general transcription initiation factor subunit Rrn7 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596129.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UST5
    Conserved Domains (1) summary
    pfam11781
    Location:10 → 37
    RRN7; RNA polymerase I-specific transcription initiation factor Rrn7
Nucleotide Protein
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