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leu1 3-isopropylmalate dehydrogenase Leu1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540283, updated on 18-Sep-2024

Summary

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Official Symbol
leu1
Official Full Name
3-isopropylmalate dehydrogenase Leu1
Primary source
PomBase:SPBC1A4.02c
Locus tag
SPOM_SPBC1A4.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC1E8.07c
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Genomic context

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See leu1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1974390..1975674, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein knh4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex substrate recognition subunit Apc10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA topoisomerase II

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The primary structure of the leu1+ gene of Schizosaccharomyces pombe. Kikuchi Y, et al. Curr Genet, 1988 Oct. PMID 3063400
  2. Actin assembly requirements of the formin Fus1 to build the fusion focus. Billault-Chaumartin I, et al. J Cell Sci, 2022 Jul 1. PMID 35673994, Free PMC Article
  3. The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones. Martínez P, et al. J Cell Sci, 2000 Dec. PMID 11069779
  4. Multiple fungal enzymes possess cysteine synthase activity in vitro. Brzywczy J, et al. Res Microbiol, 2007 Jun. PMID 17482430
  5. Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin. Weisman R, et al. Genetics, 2005 Feb. PMID 15466417, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 3-isopropylmalate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-isopropylmalate dehydrogenase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-leucine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-leucine biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol IGI
Inferred from Genetic Interaction
more info
 PubMed 

General protein information

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Preferred Names
3-isopropylmalate dehydrogenase Leu1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1974390..1975674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021706.4 → NP_595804.2  3-isopropylmalate dehydrogenase Leu1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595804.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P18869, Q76PD7
    Conserved Domains (1) summary
    TIGR00169
    Location:5 → 367
    leuB; 3-isopropylmalate dehydrogenase
Nucleotide Protein
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