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pep12 SNARE Pep12 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540289, updated on 22-Jun-2024

Summary

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Gene symbol
pep12
Gene description
SNARE Pep12
Locus tag
SPOM_SPBC31E1.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPBC31E1.04
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Genomic context

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See pep12 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (245510..247128)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene P-type calcium transport ATPase Pmr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-like protein modifier Hub1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleoporin Gle1 Neighboring gene GTP-binding protein Bms1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe Pep12p is required for vacuolar protein transport and vacuolar homotypic fusion. Hosomi A, et al. J Biosci Bioeng, 2011 Oct. PMID 21757403
  2. Mutation of the membrane-associated M1 protease APM1 results in distinct embryonic and seedling developmental defects in Arabidopsis. Peer WA, et al. Plant Cell, 2009 Jun. PMID 19531600, Free PMC Article
  3. Identification of a SNARE protein required for vacuolar protein transport in Schizosaccharomyces pombe. Takegawa K, et al. Biochem Biophys Res Commun, 2003 Nov 7. PMID 14575697
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Golgi to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi to vacuole transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle docking IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in late endosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SNARE Pep12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    245510..247128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021007.3 → NP_595100.2  SNARE Pep12 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595100.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94651
    Conserved Domains (4) summary
    COG5325
    Location:1 → 261
    COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]
    cd15840
    Location:172 → 229
    SNARE_Qa; SNARE motif, subgroup Qa
    pfam05739
    Location:205 → 256
    SNARE; SNARE domain
    cl00143
    Location:14 → 116
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
Nucleotide Protein
Heading Accession and Version

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