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apl1 AP-2 adaptor complex subunit Apl1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540375, updated on 18-Sep-2024

Summary

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Official Symbol
apl1
Official Full Name
AP-2 adaptor complex subunit Apl1
Primary source
PomBase:SPBC2G2.06c
Locus tag
SPOM_SPBC2G2.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See apl1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003423.3 (3443225..3446364, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene translocon beta subunit Sbh1 Neighboring gene mitochondrial matrix protein, YjgF family protein Mmf1, reactive intermediate imine deaminase A homolog Mmf1 Neighboring gene 60S ribosomal protein uL13 Neighboring gene ncRNA Neighboring gene mitochondrial 37S ribosomal protein bS1m Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [The alp1-1315 mutation of the tubulin-folding cofactor D gene delays the mitosis initiation in cdc25-22 mutant cells of Schizosaccharomyces pombe]. Fedianina OS. Genetika, 2010 Mar. PMID 20391777
  2. The AP-2 complex is required for proper temporal and spatial dynamics of endocytic patches in fission yeast. de León N, et al. Mol Microbiol, 2016 May. PMID 26749213
  3. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
  4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The alp1-1315 mutation of the tubulin-folding cofactor D gene delays the mitosis initiation in cdc25-22 mutant cells of Schizosaccharomyces pombe
    Title: [The alp1-1315 mutation of the tubulin-folding cofactor D gene delays the mitosis initiation in cdc25-22 mutant cells of Schizosaccharomyces pombe].
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to clathrin adaptor activity IC
Inferred by Curator
more info
  
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in clathrin-dependent endocytosis IC
Inferred by Curator
more info
  
involved_in intracellular protein transport IC
Inferred by Curator
more info
  
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of AP-2 adaptor complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
AP-2 adaptor complex subunit Apl1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3443225..3446364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022354.3 → NP_596435.1  AP-2 adaptor complex subunit Apl1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596435.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O43005
    Conserved Domains (3) summary
    COG5096
    Location:11 → 677
    COG5096; Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]
    pfam12717
    Location:100 → 266
    Cnd1; non-SMC mitotic condensation complex subunit 1
    sd00044
    Location:88 → 116
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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