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alp4 gamma tubulin complex GCP2 subunit Alp4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540392, updated on 22-Jun-2024

Summary

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Gene symbol
alp4
Gene description
gamma tubulin complex GCP2 subunit Alp4
Locus tag
SPOM_SPBC365.15
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPBC365.15
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Genomic context

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See alp4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2524061..2527134)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene UDP-glucose 4-epimerase Uge1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The carboxy-terminus of Alp4 alters microtubule dynamics to induce oscillatory nuclear movement led by the spindle pole body in Schizosaccharomyces pombe. Masuda H, et al. Genes Cells, 2006 Apr. PMID 16611238
  2. Gamma-tubulin complex-mediated anchoring of spindle microtubules to spindle-pole bodies requires Msd1 in fission yeast. Toya M, et al. Nat Cell Biol, 2007 Jun. PMID 17486116
  3. Effects of {gamma}-tubulin complex proteins on microtubule nucleation and catastrophe in fission yeast. Zimmerman S, et al. Mol Biol Cell, 2005 Jun. PMID 15772152, Free PMC Article
  4. Rsp1p, a J domain protein required for disassembly and assembly of microtubule organizing centers during the fission yeast cell cycle. Zimmerman S, et al. Dev Cell, 2004 Apr. PMID 15068790
  5. The XMAP215 Ortholog Alp14 Promotes Microtubule Nucleation in Fission Yeast. Flor-Parra I, et al. Curr Biol, 2018 Jun 4. PMID 29779879, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables gamma-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to microtubule minus-end binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to microtubule nucleator activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in astral microtubule anchoring at mitotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cytoplasmic microtubule organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic microtubule organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule nucleation IC
Inferred by Curator
more info
 PubMed 
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic spindle assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear migration by microtubule mediated pushing forces IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in equatorial microtubule organizing center IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in equatorial microtubule organizing center IDA
Inferred from Direct Assay
more info
 PubMed 
part_of gamma-tubulin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of gamma-tubulin ring complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of gamma-tubulin small complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in half bridge of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in inner plaque of mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in interphase microtubule organizing center IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in meiotic spindle pole body EXP
Inferred from Experiment
more info
 PubMed 
is_active_in meiotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in mitotic spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in old mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
gamma tubulin complex GCP2 subunit Alp4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2524061..2527134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021954.3 → NP_596044.1  gamma tubulin complex GCP2 subunit Alp4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596044.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9Y705
    Conserved Domains (1) summary
    pfam04130
    Location:74 → 693
    Spc97_Spc98; Spc97 / Spc98 family
Nucleotide Protein
Heading Accession and Version

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