U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

spt7 SAGA complex bromodomain subunit Spt7 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540408, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
spt7
Official Full Name
SAGA complex bromodomain subunit Spt7
Primary source
PomBase:SPBC25H2.11c
Locus tag
SPOM_SPBC25H2.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See spt7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003423.3 (3263270..3266875)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene DNA polymerase epsilon catalytic subunit Pol2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene chaperonin-containing T-complex eta subunit Cct7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA acetyltransferase Neighboring gene protein Mic19

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes. Cohen A, et al. PLoS Genet, 2022 Feb. PMID 35157728, Free PMC Article
  2. Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin. Bao K, et al. Genes Dev, 2019 Jan 1. PMID 30573453, Free PMC Article
  3. The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Helmlinger D, et al. Genes Dev, 2008 Nov 15. PMID 19056896, Free PMC Article
  4. Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. Helmlinger D, et al. EMBO J, 2011 Jun 3. PMID 21642955, Free PMC Article
  5. TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability. Laboucarié T, et al. EMBO Rep, 2017 Dec. PMID 29079657, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to transcription coactivator activity IC
Inferred by Curator
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SAGA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in pericentric heterochromatin EXP
Inferred from Experiment
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
SAGA complex bromodomain subunit Spt7

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3263270..3266875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022276.3 → NP_596356.2  SAGA complex bromodomain subunit Spt7 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596356.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87152
    Conserved Domains (3) summary
    cd05510
    Location:309 → 420
    Bromo_SPT7_like; Bromodomain; SPT7_like subfamily. SPT7 is a yeast protein that functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, and SLIK. SAGA is involved in the RNA polymerase II-dependent transcriptional ...
    COG5076
    Location:161 → 554
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    pfam07524
    Location:707 → 783
    Bromo_TP; Bromodomain associated
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials