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rhp23 UV excision repair protein rhp23 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540481, updated on 18-Sep-2024

Summary

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Official Symbol
rhp23
Official Full Name
UV excision repair protein rhp23
Primary source
PomBase:SPBC2D10.12
Locus tag
SPOM_SPBC2D10.12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rhp23 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003423.3 (2986929..2988489)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleosome assembly protein Nap2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene telomerase regulator Est1 Neighboring gene myosin type V

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ubiquitin-associated (UBA) 1 domain of Schizosaccharomyces pombe Rhp23 is essential for the recognition of ubiquitin-proteasome system substrates both in vitro and in vivo. Medina B, et al. J Biol Chem, 2012 Dec 7. PMID 23038266, Free PMC Article
  2. Identification and characterization of the rhp23(+) DNA repair gene in Schizosaccharomyces pombe. Lombaerts M, et al. Biochem Biophys Res Commun, 2000 Feb 5. PMID 10652237
  3. Characterisation of the nascent polypeptide-associated complex in fission yeast. Andersen KM, et al. Mol Biol Rep, 2007 Dec. PMID 17211518
  4. Two budding yeast RAD4 homologs in fission yeast play different roles in the repair of UV-induced DNA damage. Fukumoto Y, et al. DNA Repair (Amst), 2002 Oct 1. PMID 12531030
  5. Involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination. Elder RT, et al. Nucleic Acids Res, 2002 Jan 15. PMID 11788722, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. internal Rhp23 UBA1 domain provides sufficient Ub recognition for the protein to function without UBA2.
    Title: The ubiquitin-associated (UBA) 1 domain of Schizosaccharomyces pombe Rhp23 is essential for the recognition of ubiquitin-proteasome system substrates both in vitro and in vivo.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables damaged DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in ERAD pathway ISO
Inferred from Sequence Orthology
more info
  
involved_in nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nuclear envelope HDA PubMed 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
UV excision repair protein rhp23

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2986929..2988489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022151.3 → NP_596231.1  UV excision repair protein rhp23 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596231.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74803
    Conserved Domains (5) summary
    cd01805
    Location:1 → 76
    RAD23_N; Ubiquitin-like domain of RAD23
    cd14378
    Location:141 → 187
    UBA1_Rhp23p_like; UBA1 domain of Schizosaccharomyces pombe UV excision repair protein Rhp23p and its homologs
    cd14381
    Location:321 → 360
    UBA2_Rhp23p_like; UBA2 domain of Schizosaccharomyces pombe UV excision repair protein Rhp23p and its fungal homologs
    TIGR00601
    Location:1 → 363
    rad23; UV excision repair protein Rad23
    pfam09280
    Location:247 → 302
    XPC-binding; XPC-binding domain
Nucleotide Protein
Heading Accession and Version

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