U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ltc1 sterol transfer protein Ltc1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540703, updated on 22-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
ltc1
Gene description
sterol transfer protein Ltc1
Locus tag
SPOM_SPBC20F10.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
lam6
Old locus tag
SPBC20F10.07
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ltc1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3295640..3298548)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene NRDE-2 family protein Neighboring gene mitotic spindle checkpoint protein Mad2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase II nuclear import protein Rtp1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition. Marek M, et al. J Cell Biol, 2020 Jun 1. PMID 32320462, Free PMC Article
  2. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  3. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables lipid binding EXP
Inferred from Experiment
more info
 PubMed 
enables sterol binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sterol transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sterol transfer activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in intermembrane sterol transfer EXP
Inferred from Experiment
more info
 PubMed 
involved_in intracellular sterol transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cortical endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-plasma membrane contact site IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-plasma membrane contact site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus-vacuole junction ISO
Inferred from Sequence Orthology
more info
  
is_active_in perinuclear endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
sterol transfer protein Ltc1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3295640..3298548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022292.3 → NP_596371.1  sterol transfer protein Ltc1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596371.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42976, Q9USA4
    Conserved Domains (2) summary
    cd13220
    Location:208 → 301
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:435 → 575
    DUF4782; Domain of unknown function (DUF4782)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials