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sap61 U2 snRNP-associated protein sap61 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540932, updated on 18-Sep-2024

Summary

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Official Symbol
sap61
Official Full Name
U2 snRNP-associated protein sap61
Primary source
PomBase:SPBC36.09
Locus tag
SPOM_SPBC36.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sap61 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (858476..860614)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ER farnesyl pyrophosphate synthetase Erg20 Neighboring gene COG complex subunit Cog2 Neighboring gene elongator subunit Iki3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene phosphatidic acid transfer protein Ups2 Neighboring gene SGT1-like protein Git7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
  2. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
  3. The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. Kallgren SP, et al. PLoS Genet, 2014. PMID 24874881, Free PMC Article
  4. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
  5. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of U2 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U2-type prespliceosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
U2 snRNP-associated protein sap61

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    858476..860614
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021245.3 → NP_595337.1  U2 snRNP-associated protein sap61 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595337.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O59706
    Conserved Domains (5) summary
    smart00451
    Location:240 → 274
    ZnF_U1; U1-like zinc finger
    COG5188
    Location:3 → 492
    PRP9; Splicing factor 3a, subunit 3 [RNA processing and modification]
    pfam11931
    Location:299 → 489
    DUF3449; Domain of unknown function (DUF3449)
    pfam12108
    Location:75 → 101
    SF3a60_bindingd; Splicing factor SF3a60 binding domain
    pfam16837
    Location:126 → 200
    SF3A3; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
Nucleotide Protein
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