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spo14 GDP/GTP exchange factor Spo14 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540996, updated on 18-Sep-2024

Summary

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Official Symbol
spo14
Official Full Name
GDP/GTP exchange factor Spo14
Primary source
PomBase:SPBC3H7.01
Locus tag
SPOM_SPBC3H7.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBP16F5.01c; stl1
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Genomic context

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See spo14 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003423.3 (1889972..1891843, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene sulfate transporter Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIIH complex cyclin Mcs2 Neighboring gene SAGA complex, phosphatidylinositol pseudokinase subunit Tra1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Live observation of forespore membrane formation in fission yeast. Nakamura T, et al. Mol Biol Cell, 2008 Aug. PMID 18550796, Free PMC Article
  2. The fission yeast spo14+ gene encoding a functional homologue of budding yeast Sec12 is required for the development of forespore membranes. Nakamura-Kubo M, et al. Mol Biol Cell, 2003 Mar. PMID 12631727, Free PMC Article
  3. Structural modification of spindle pole bodies during meiosis II is essential for the normal formation of ascospores in Schizosaccharomyces pombe: ultrastructural analysis of spo mutants. Hirata A, et al. Yeast, 1994 Feb. PMID 8203159
  4. A fission yeast SNAP-25 homologue, SpSec9, is essential for cytokinesis and sporulation. Nakamura T, et al. Cell Struct Funct, 2005. PMID 16272747
  5. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in ascospore formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ascospore-type prospore assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ascospore-type prospore membrane formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of COPII vesicle coating IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
GDP/GTP exchange factor Spo14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1889972..1891843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356237.2 → NP_001342743.1  GDP/GTP exchange factor Spo14 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10659, Q9HFE9
    Conserved Domains (2) summary
    sd00039
    Location:167 → 199
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:112 → 324
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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