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rga1 Rho-type GTPase-activating protein Rga1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541022, updated on 18-Sep-2024

Summary

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Official Symbol
rga1
Official Full Name
Rho-type GTPase-activating protein Rga1
Primary source
PomBase:SPBC3F6.05
Locus tag
SPOM_SPBC3F6.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See rga1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (4196047..4200033)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glucosyltransferase Alg6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of GTPase-activating proteins for the function of the Rho-family small GTPases in the fission yeast Schizosaccharomyces pombe. Nakano K, et al. Genes Cells, 2001 Dec. PMID 11737264
  2. Pom1 DYRK regulates localization of the Rga4 GAP to ensure bipolar activation of Cdc42 in fission yeast. Tatebe H, et al. Curr Biol, 2008 Mar 11. PMID 18328707, Free PMC Article
  3. Rgf1p is a specific Rho1-GEF that coordinates cell polarization with cell wall biogenesis in fission yeast. García P, et al. Mol Biol Cell, 2006 Apr. PMID 16421249, Free PMC Article
  4. Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast. Mutoh T, et al. Genes Cells, 2005 Dec. PMID 16324155
  5. Feedback regulation of SIN by Etd1 and Rho1 in fission yeast. Alcaide-Gavilán M, et al. Genetics, 2014 Feb. PMID 24336750, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTPase activator activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables GTPase activator activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell wall organization or biogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in division septum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Rho-type GTPase-activating protein Rga1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    4196047..4200033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023763.3 → NP_596743.1  Rho-type GTPase-activating protein Rga1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596743.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O43052
    Conserved Domains (4) summary
    cd09391
    Location:116 → 172
    LIM1_Lrg1p_like; The first LIM domain of Lrg1p, a LIM and RhoGap domain containing protein
    cd09392
    Location:180 → 232
    LIM2_Lrg1p_like; The second LIM domain of Lrg1p, a LIM and RhoGap domain containing protein
    cd04397
    Location:835 → 1044
    RhoGAP_fLRG1; RhoGAP_fLRG1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of fungal LRG1-like proteins. Yeast Lrg1p is required for efficient cell fusion, and mother-daughter cell separation, possibly through acting as a RhoGAP specifically ...
    cl02475
    Location:485 → 539
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
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