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ccr1 NADPH-cytochrome p450 reductase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541038, updated on 18-Sep-2024

Summary

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Official Symbol
ccr1
Official Full Name
NADPH-cytochrome p450 reductase
Primary source
PomBase:SPBC29A10.01
Locus tag
SPOM_SPBC29A10.01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC365.17
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Genomic context

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See ccr1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2532975..2535594)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene meiotic RNA-binding protein 1 Neighboring gene ncRNA Neighboring gene histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex subunit A Pcf1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast. Liu Q, et al. Antimicrob Agents Chemother, 2020 Aug 20. PMID 32571823, Free PMC Article
  2. Coexpression of CPR from various origins enhances biotransformation activity of human CYPs in S. pombe. Neunzig I, et al. Appl Biochem Biotechnol, 2013 Aug. PMID 23737303
  3. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article
  4. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
  5. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast.
    Title: NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables FMN binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables NADPH-hemoprotein reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADPH-hemoprotein reductase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables NADPH-hemoprotein reductase activity TAS
Traceable Author Statement
more info
 PubMed 
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ergosterol biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NADPH-cytochrome p450 reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2532975..2535594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021956.3 → NP_596046.1  NADPH-cytochrome p450 reductase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596046.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P36587, Q9USU6, Q9UU68
    Conserved Domains (3) summary
    cd06204
    Location:264 → 678
    CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
    COG0369
    Location:18 → 678
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    pfam00258
    Location:55 → 203
    Flavodoxin_1; Flavodoxin
Nucleotide Protein
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