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egt2 ergothioneine biosynthesis methyltransferase Egt2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541092, updated on 22-Jun-2024

Summary

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Gene symbol
egt2
Gene description
ergothioneine biosynthesis methyltransferase Egt2
Locus tag
SPOM_SPBC660.12C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPBC660.12c
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Genomic context

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See egt2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (215522..218349, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein mug168 Neighboring gene mitochondrial translation elongation factor G Neighboring gene single-stranded telomeric-binding protein Tgc1 Neighboring gene ncRNA Neighboring gene DNA replication factor A subunit Ssb1 Neighboring gene ncRNA Neighboring gene M phase inhibitor protein kinase Mik1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system. Pluskal T, et al. PLoS One, 2014. PMID 24828577, Free PMC Article
  2. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
  3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in ergothioneine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in selenoneine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
ergothioneine biosynthesis methyltransferase Egt2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    215522..218349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020998.3 → NP_595091.1  ergothioneine biosynthesis methyltransferase Egt2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595091.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94431
    Conserved Domains (2) summary
    COG0520
    Location:23 → 390
    CsdA; Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]
    cl18945
    Location:64 → 305
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
Nucleotide Protein
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Gene LinkOut

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Molecular Biology Databases
Research Materials