U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

scl1 proteasome core particle subunit alpha 1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541139, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
scl1
Official Full Name
proteasome core particle subunit alpha 1
Primary source
PomBase:SPBC646.16
Locus tag
SPOM_SPBC646.16
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See scl1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (957634..958637)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene origin recognition complex subunit Orc5 Neighboring gene ncRNA Neighboring gene Pex16 family peroxisome import protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene meiotic dynein intermediate chain Dic1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Lasker K, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307589, Free PMC Article
  2. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Bohn S, et al. Proc Natl Acad Sci U S A, 2010 Dec 7. PMID 21098295, Free PMC Article
  3. Suppressor screening reveals common kleisin-hinge interaction in condensin and cohesin, but different modes of regulation. Xu X, et al. Proc Natl Acad Sci U S A, 2019 May 28. PMID 31072933, Free PMC Article
  4. Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast. Takeda K, et al. Proc Natl Acad Sci U S A, 2010 Feb 23. PMID 20133687, Free PMC Article
  5. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. Kouranti I, et al. PLoS Biol, 2010 Sep 7. PMID 20838651, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to endopeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proteasome core complex, alpha-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proteasome core complex, alpha-subunit complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
proteasome core particle subunit alpha 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    957634..958637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021282.3 → NP_595374.1  proteasome core particle subunit alpha 1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595374.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94517
    Conserved Domains (2) summary
    COG0638
    Location:5 → 243
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03754
    Location:6 → 219
    proteasome_alpha_type_6; proteasome_alpha_type_6. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.