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ubp14 ubiquitin hydrolase Ubp14 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541157, updated on 18-Sep-2024

Summary

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Official Symbol
ubp14
Official Full Name
ubiquitin hydrolase Ubp14
Primary source
PomBase:SPBC6B1.06c
Locus tag
SPOM_SPBC6B1.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ubp14 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (2637329..2640029, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene microtubule-site clamp monopolin complex subunit Mde4 Neighboring gene E1 Atg8 and Atg12 E1 activating enzyme Atg7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone H2B ubiquitination promotes the function of the anaphase-promoting complex/cyclosome in Schizosaccharomyces pombe. Elmore ZC, et al. G3 (Bethesda), 2014 Jun 19. PMID 24948786, Free PMC Article
  2. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. Kouranti I, et al. PLoS Biol, 2010 Sep 7. PMID 20838651, Free PMC Article
  3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables K48-linked deubiquitinase activity HDA PubMed 
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein stability IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
NOT is_active_in nucleolus HDA PubMed 
is_active_in nucleoplasm HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin hydrolase Ubp14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2637329..2640029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021999.3 → NP_596085.1  ubiquitin hydrolase Ubp14 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596085.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q11119
    Conserved Domains (6) summary
    smart00290
    Location:24 → 77
    ZnF_UBP; Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
    COG5207
    Location:1 → 774
    UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
    cd02658
    Location:301 → 772
    Peptidase_C19B; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd14297
    Location:642 → 680
    UBA2_spUBP14_like; UBA2 domain found in Schizosaccharomyces pombe ubiquitin carboxyl-terminal hydrolase 14 (spUBP14) and similar proteins
    cd14385
    Location:578 → 624
    UBA1_spUBP14_like; UBA1 domain found in Schizosaccharomyces pombe ubiquitin carboxyl-terminal hydrolase 14 (spUBP14) and similar proteins
    pfam02148
    Location:174 → 247
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
Nucleotide Protein
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