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hht2 histone H3 h3.2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541220, updated on 22-Jun-2024

Summary

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Gene symbol
hht2
Gene description
histone H3 h3.2
Locus tag
SPOM_SPBC8D2.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
h3.2
Old locus tag
SPBC8D2.04
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Genomic context

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See hht2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1365119..1365818)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene histone H4 h4.2 Neighboring gene protein Sfi1 Neighboring gene ncRNA Neighboring gene isoleucine--tRNA(Ile) ligase Irs1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast. Lim KK, et al. Sci Rep, 2015 Sep 15. PMID 26369364, Free PMC Article
  2. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. Dhayalan A, et al. J Biol Chem, 2010 Aug 20. PMID 20547484, Free PMC Article
  3. Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Canzio D, et al. Mol Cell, 2011 Jan 7. PMID 21211724, Free PMC Article
  4. Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe. Xhemalce B, et al. J Biol Chem, 2007 May 18. PMID 17369611
  5. Establishment and maintenance of a heterochromatin domain. Hall IM, et al. Science, 2002 Sep 27. PMID 12215653

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Schizosaccharomyces pombe Hst4, a homolog of histone deacetylase Sir2, participates in S-phase-specific DNA damage tolerance; it was required for the deacetylation of histone H3 core domain residue lysine 56.
    Title: Schizosaccharomyces pombe Hst4 functions in DNA damage response by regulating histone H3 K56 acetylation.
  2. Clr4 abolished the inhibitory effect of histone h3 on the RanGAP activity required for the heterochromatin assembly.
    Title: Nuclear RanGAP is required for the heterochromatin assembly and is reciprocally regulated by histone H3 and Clr4 histone methyltransferase in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding ISM
Inferred from Sequence Model
more info
  
enables chromatin-protein adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables chromatin-protein adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of chromatin IC
Inferred by Curator
more info
  
Process Evidence Code Pubs
involved_in DNA damage response IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in heterochromatin boundary formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in heterochromatin formation EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitotic sister chromatid biorientation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pericentric heterochromatin formation EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mating-type region heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolar peripheral inclusion body IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nucleosome ISM
Inferred from Sequence Model
more info
  
is_active_in nucleus EXP
Inferred from Experiment
more info
 PubMed 
is_active_in nucleus HDA PubMed 
part_of pericentric heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
part_of subtelomeric heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
histone H3 h3.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1365119..1365818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021462.3 → NP_595567.1  histone H3 h3.2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595567.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P09988, P10651
    Conserved Domains (2) summary
    PTZ00018
    Location:1 → 136
    PTZ00018; histone H3; Provisional
    pfam00125
    Location:1 → 132
    Histone; Core histone H2A/H2B/H3/H4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
1202262D.1

Gene LinkOut

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