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lid2 Lid2 complex histone demethylase subunit Lid2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541299, updated on 18-Sep-2024

Summary

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Official Symbol
lid2
Official Full Name
Lid2 complex histone demethylase subunit Lid2
Primary source
PomBase:SPBP19A11.06
Locus tag
SPOM_SPBP19A11.06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBP4H10.01
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Genomic context

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See lid2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2863808..2868411)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein bL27m Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Li F, et al. Cell, 2008 Oct 17. PMID 18957202, Free PMC Article
  2. High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. Roguev A, et al. J Biol Chem, 2003 Mar 7. PMID 12488447
  3. A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Roguev A, et al. Mol Cell Proteomics, 2004 Feb. PMID 14617822
  4. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding ISM
Inferred from Sequence Model
more info
  
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity EXP
Inferred from Experiment
more info
 PubMed 
enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in heterochromatin boundary formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulatory ncRNA-mediated heterochromatin formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Lid2 complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mating-type region heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in pericentric heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Lid2 complex histone demethylase subunit Lid2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2863808..2868411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022094.3 → NP_596174.1  Lid2 complex histone demethylase subunit Lid2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596174.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9HDV4, Q9P7E6
    Conserved Domains (7) summary
    smart01014
    Location:122 → 208
    ARID; ARID/BRIGHT DNA binding domain
    cd15518
    Location:1098 → 1142
    PHD_Ecm5p_Lid2p_like; PHD finger found in Saccharomyces cerevisiae extracellular matrix protein 5 (Ecm5p), Schizosaccharomyces pombe Lid2 complex component Lid2p, and similar proteins
    cd15519
    Location:270 → 315
    PHD1_Lid2p_like; PHD finger 1 found in Schizosaccharomyces pombe Lid2 complex component Lid2p and similar proteins
    cd15520
    Location:1354 → 1400
    PHD3_Lid2p_like; PHD finger 3 found in Schizosaccharomyces pombe Lid2 complex component Lid2p and similar proteins
    pfam02928
    Location:646 → 697
    zf-C5HC2; C5HC2 zinc finger
    pfam08429
    Location:710 → 1047
    PLU-1; PLU-1-like protein
    cl21464
    Location:441 → 557
    cupin_like; Conserved domain found in cupin and related proteins
Nucleotide Protein
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