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lcf2 long-chain-fatty-acid-CoA ligase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541350, updated on 22-Jun-2024

Summary

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Gene symbol
lcf2
Gene description
long-chain-fatty-acid-CoA ligase
Locus tag
SPOM_SPBP4H10.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Old locus tag
SPBP4H10.11c
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Genomic context

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See lcf2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2892129..2894818, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcription repressor Rsv1 Neighboring gene mitochondrial rhomboid family peptidase Rbd3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein with a role in ER insertion of tail-anchored membrane proteins

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a fatty acyl-CoA synthetase gene, lcf2+, which affects viability after entry into the stationary phase in Schizosaccharomyces pombe. Fujita Y, et al. Biosci Biotechnol Biochem, 2007 Dec. PMID 18071249
  2. Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF. Tafforeau L, et al. EMBO J, 2006 Oct 4. PMID 17016471, Free PMC Article
  3. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
  4. Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis. Snaith HA, et al. J Cell Sci, 2011 Jul 1. PMID 21652630, Free PMC Article
  5. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. We present evidence that the gene SPBP4H10.11c (named lcf2(+)), encodes a new fatty acyl-CoA synthetase.
    Title: Identification of a fatty acyl-CoA synthetase gene, lcf2+, which affects viability after entry into the stationary phase in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables myristoyl-CoA ligase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty-acyl-CoA metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in fungal-type vacuole membrane HDA PubMed 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
long-chain-fatty-acid-CoA ligase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2892129..2894818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022104.3 → NP_596185.1  long-chain-fatty-acid-CoA ligase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596185.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7D7
    Conserved Domains (2) summary
    cd05927
    Location:96 → 685
    LC-FACS_euk; Eukaryotic long-chain fatty acid CoA synthetase (LC-FACS)
    COG1022
    Location:54 → 689
    FAA1; Long-chain acyl-CoA synthetase (AMP-forming) [Lipid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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