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atg8 autophagy-associated protein Atg8 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541386, updated on 18-Sep-2024

Summary

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Official Symbol
atg8
Official Full Name
autophagy-associated protein Atg8
Primary source
PomBase:SPBP8B7.24c
Locus tag
SPOM_SPBP8B7.24C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See atg8 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (3684281..3685370, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase E3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp4 Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe Homologs of Human DJ-1 Are Stationary Phase-Associated Proteins That Are Involved in Autophagy and Oxidative Stress Resistance. Su Y, et al. PLoS One, 2015. PMID 26624998, Free PMC Article
  2. Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast. Fukuda T, et al. Elife, 2020 Nov 3. PMID 33138913, Free PMC Article
  3. Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein. Liu XM, et al. Elife, 2018 Nov 19. PMID 30451685, Free PMC Article
  4. A UPR-Induced Soluble ER-Phagy Receptor Acts with VAPs to Confer ER Stress Resistance. Zhao D, et al. Mol Cell, 2020 Sep 17. PMID 32735772
  5. Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance. Mikawa T, et al. Genes Cells, 2010 Mar. PMID 20070859

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables phosphatidylethanolamine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in autophagosome maturation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to nitrogen starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in macroautophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in membrane fusion ISO
Inferred from Sequence Orthology
more info
  
involved_in mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vacuole organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in autophagosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in fungal-type vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in fungal-type vacuole membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in phagophore assembly site IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
autophagy-associated protein Atg8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3684281..3685370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022452.3 → NP_596531.1  autophagy-associated protein Atg8 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596531.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94272
    Conserved Domains (1) summary
    cd01611
    Location:5 → 116
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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