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thi5 DNA-binding transcription factor Thi5 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541388, updated on 18-Sep-2024

Summary

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Official Symbol
thi5
Official Full Name
DNA-binding transcription factor Thi5
Primary source
PomBase:SPBP8B7.30c
Locus tag
SPOM_SPBP8B7.30C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See thi5 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3694964..3697705, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene para-aminobenzoate synthase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene acid phosphatase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Joint regulation of the nmt1 promoter and sporulation by Thi1 and Thi5 in Schizosaccharomyces pombe. McQuire TA, et al. Curr Genet, 2006 Oct. PMID 16874521
  2. Computational prediction of membrane-tethered transcription factors. Zupicich J, et al. Genome Biol, 2001. PMID 11790253, Free PMC Article
  3. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
  4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Thi5 works in the same pathway as of Thi1 to positively regulate nmt1 promoter activity
    Title: Joint regulation of the nmt1 promoter and sporulation by Thi1 and Thi5 in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific EXP
Inferred from Experiment
more info
 PubMed 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISM
Inferred from Sequence Model
more info
  
enables zinc ion binding ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in positive regulation of thiamine biosynthetic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcription factor Thi5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3694964..3697705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022458.3 → NP_596537.1  DNA-binding transcription factor Thi5 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596537.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94278
    Conserved Domains (2) summary
    cd12148
    Location:330 → 706
    fungal_TF_MHR; fungal transcription factor regulatory middle homology region
    smart00066
    Location:32 → 73
    GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
Nucleotide Protein
Heading Accession and Version

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