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mrf1 peptide chain release factor [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541478, updated on 14-Nov-2024

Summary

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Official Symbol
mrf1
Official Full Name
peptide chain release factor
Primary source
PomBase:SPAC2F7.17
Locus tag
SPOM_SPAC2F7.17
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mrf1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (570168..571876)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene phospholipase D Pld1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putatiRho-type GTPase-activating protein Rga8 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria. Dujeancourt L, et al. Mitochondrion, 2013 Nov. PMID 23892058, Free PMC Article
  2. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
  4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables translation release factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitochondrial translational termination ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrial matrix IC
Inferred by Curator
more info
  

General protein information

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Preferred Names
peptide chain release factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    570168..571876
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018387.3 → NP_592987.1  peptide chain release factor [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592987.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09691
    Conserved Domains (3) summary
    COG0216
    Location:11 → 396
    PrfA; Protein chain release factor A [Translation, ribosomal structure and biogenesis]
    pfam00472
    Location:253 → 354
    RF-1; RF-1 domain
    pfam03462
    Location:66 → 237
    PCRF; PCRF domain
Nucleotide Protein
Heading Accession and Version

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