U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ofd2 2-oxoglutarate-Fe(2+) oxygenase superfamily protein Ofd2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541495, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
ofd2
Official Full Name
2-oxoglutarate-Fe(2+) oxygenase superfamily protein Ofd2
Primary source
PomBase:SPAP8A3.02c
Locus tag
SPOM_SPAP8A3.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ofd2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5315471..5316640, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL22 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ZIP zinc transporter 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia. Lando D, et al. PLoS One, 2012. PMID 22235339, Free PMC Article
  2. Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones. Korvald H, et al. PLoS One, 2011. PMID 21949882, Free PMC Article
  3. Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member. Hughes BT, et al. EMBO J, 2008 May 21. PMID 18418381, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ofd2 as a histone H2A dioxygenase enzyme
    Title: The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 2-oxoglutarate-dependent dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2-oxoglutarate-dependent dioxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to hypoxia IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
NOT is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
2-oxoglutarate-Fe(2+) oxygenase superfamily protein Ofd2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5315471..5316640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020372.3 → NP_594941.1  2-oxoglutarate-Fe(2+) oxygenase superfamily protein Ofd2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594941.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UT12
    Conserved Domains (1) summary
    COG3145
    Location:1 → 196
    AlkB; Alkylated DNA repair dioxygenase AlkB [Replication, recombination and repair]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials