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pabp major poly(A) binding protein Pabp/Pab1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541505, updated on 18-Sep-2024

Summary

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Official Symbol
pabp
Official Full Name
major poly(A) binding protein Pabp/Pab1
Primary source
PomBase:SPAC57A7.04c
Locus tag
SPOM_SPAC57A7.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pab1; pab11
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Genomic context

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See pabp in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1542786..1545221)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene homocysteine methyltransferase Neighboring gene ncRNA Neighboring gene U3 snoRNP protein Utp14 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The stress granule protein Vgl1 and poly(A)-binding protein Pab1 are required for doxorubicin resistance in the fission yeast Schizosaccharomyces pombe. Morita T, et al. Biochem Biophys Res Commun, 2012 Jan 6. PMID 22172946
  2. Schizosaccharomyces pombe spPABP, a homologue of Saccharomyces cerevisiae Pab1p, is a non-essential, shuttling protein that facilitates mRNA export. Thakurta AG, et al. Yeast, 2002 Jun 30. PMID 12112233
  3. Dicer and Hsp104 function in a negative feedback loop to confer robustness to environmental stress. Oberti D, et al. Cell Rep, 2015 Jan 6. PMID 25543137
  4. Cellular stress induces cytoplasmic RNA granules in fission yeast. Nilsson D, et al. RNA, 2011 Jan. PMID 21098141, Free PMC Article
  5. mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Webster MW, et al. Mol Cell, 2018 Jun 21. PMID 29932902, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(A) binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA 3'-end processing ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear-transcribed mRNA poly(A) tail shortening IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of nuclear-transcribed mRNA poly(A) tail shortening ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of post-mRNA release spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
major poly(A) binding protein Pabp/Pab1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1542786..1545221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018809.3 → NP_593377.1  major poly(A) binding protein Pabp/Pab1 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P31209, P87135
    Conserved Domains (6) summary
    TIGR01628
    Location:80 → 642
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    smart00517
    Location:581 → 644
    PolyA; C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein
    cd12378
    Location:81 → 160
    RRM1_I_PABPs; RNA recognition motif 1 in type I polyadenylate-binding proteins
    cd12379
    Location:166 → 242
    RRM2_I_PABPs; RNA recognition motif 2 found in type I polyadenylate-binding proteins
    cd12380
    Location:260 → 339
    RRM3_I_PABPs; RNA recognition motif 3 found in type I polyadenylate-binding proteins
    cd12381
    Location:363 → 441
    RRM4_I_PABPs; RNA recognition motif 4 in type I polyadenylate-binding proteins
Nucleotide Protein
Heading Accession and Version

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