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csn4 COP9/signalosome complex subunit Csn4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541517, updated on 18-Sep-2024

Summary

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Official Symbol
csn4
Official Full Name
COP9/signalosome complex subunit Csn4
Primary source
PomBase:SPAC22A12.03c
Locus tag
SPOM_SPAC22A12.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See csn4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1160118..1161425, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene DNA 5' exonuclease Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein mug103 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS8 Neighboring gene DNA-directed RNA polymerase III complex subunit Rpc11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability. Wee S, et al. Nat Cell Biol, 2005 Apr. PMID 15793566
  2. The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p. Zhou C, et al. BMC Biochem, 2001. PMID 11504566, Free PMC Article
  3. Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes. Mundt KE, et al. Mol Biol Cell, 2002 Feb. PMID 11854407, Free PMC Article
  4. Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase. Liu C, et al. EMBO J, 2005 Nov 16. PMID 16252005, Free PMC Article
  5. CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire. Wu S, et al. Nat Commun, 2013. PMID 23535663, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
COP9/signalosome complex subunit Csn4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1160118..1161425 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018630.3 → NP_593233.1  COP9/signalosome complex subunit Csn4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593233.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13895
    Conserved Domains (1) summary
    smart00753
    Location:283 → 370
    PAM; PCI/PINT associated module
Nucleotide Protein
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