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pst2 Clr6 histone deacetylase complex subunit Pst2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541624, updated on 18-Sep-2024

Summary

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Official Symbol
pst2
Official Full Name
Clr6 histone deacetylase complex subunit Pst2
Primary source
PomBase:SPAC23C11.15
Locus tag
SPOM_SPAC23C11.15
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See pst2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2160486..2164078)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ER zinc importer, CDF family, Zhf1 Neighboring gene ncRNA Neighboring gene Polo kinase Plo1 Neighboring gene ncRNA Neighboring gene putative potassium ion transporter Mdm28

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity. Nakayama J, et al. EMBO J, 2003 Jun 2. PMID 12773392, Free PMC Article
  2. CENP-C functions as a scaffold for effectors with essential kinetochore functions in mitosis and meiosis. Tanaka K, et al. Dev Cell, 2009 Sep. PMID 19758558
  3. Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast. Choi ES, et al. PLoS Genet, 2012 Sep. PMID 23028377, Free PMC Article
  4. Repression of a large number of genes requires interplay between homologous recombination and HIRA. Misova I, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33511417, Free PMC Article
  5. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nicolas E, et al. Nat Struct Mol Biol, 2007 May. PMID 17450151

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables molecular adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of Rpd3S complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Sin3-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
NOT is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Clr6 histone deacetylase complex subunit Pst2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2160486..2164078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019077.3 → NP_593646.1  Clr6 histone deacetylase complex subunit Pst2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593646.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13919
    Conserved Domains (4) summary
    COG5602
    Location:1 → 1075
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
    pfam02671
    Location:56 → 99
    PAH; Paired amphipathic helix repeat
    pfam08295
    Location:335 → 430
    Sin3_corepress; Sin3 family co-repressor
    pfam16879
    Location:744 → 1016
    Sin3a_C; C-terminal domain of Sin3a protein
Nucleotide Protein
Heading Accession and Version

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