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ace2 DNA-binding transcription factor Ace2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541661, updated on 18-Sep-2024

Summary

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Official Symbol
ace2
Official Full Name
DNA-binding transcription factor Ace2
Primary source
PomBase:SPAC6G10.12c
Locus tag
SPOM_SPAC6G10.12C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ace2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3239232..3241153, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-40S ribosomal protein S31 fusion protein Neighboring gene uncharacterized protein Neighboring gene RNA-binding protein Nop9 Neighboring gene ncRNA Neighboring gene histone H3.3 H4 heterotetramer chaperone Rtt106

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription regulation of the alpha-glucanase gene agn1 by cell separation transcription factor Ace2p in fission yeast. Dekker N, et al. FEBS Lett, 2006 May 29. PMID 16678171
  2. Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe. Alonso-Nuñez ML, et al. Mol Biol Cell, 2005 Apr. PMID 15689498, Free PMC Article
  3. Transcription factors mediate condensin recruitment and global chromosomal organization in fission yeast. Kim KD, et al. Nat Genet, 2016 Oct. PMID 27548313, Free PMC Article
  4. The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe. Mehta S, et al. FEBS Lett, 2009 Oct 6. PMID 19720063
  5. Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. Petit CS, et al. J Cell Sci, 2005 Dec 15. PMID 16317047

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Med8 mediator subunit is involved in transmitting regulatory information from Ace2 to RNA polymerase II via Rpb4.
    Title: The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe.
  2. identification of seven genes (adg1(+), adg2(+), adg3(+), cfh4(+), agn1(+), eng1(+), and mid2(+)) whose expression is induced by the transcription factor Ace2p
    Title: Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
NOT is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcription factor Ace2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3239232..3241153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019533.3 → NP_594109.1  DNA-binding transcription factor Ace2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594109.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14258
    Conserved Domains (4) summary
    COG5048
    Location:45 → 518
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:448 → 467
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:473 → 495
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:487 → 511
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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