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scd2 Cdc42 GTPase complex scaffold subunit Scd2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541726, updated on 18-Sep-2024

Summary

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Official Symbol
scd2
Official Full Name
Cdc42 GTPase complex scaffold subunit Scd2
Primary source
PomBase:SPAC22H10.07
Locus tag
SPOM_SPAC22H10.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ral3
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Genomic context

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See scd2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2382504..2385153)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene metallothionein Zym1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microscopy of Fission Yeast Sexual Lifecycle. Vjestica A, et al. J Vis Exp, 2016 Mar 9. PMID 27022830, Free PMC Article
  2. Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding. Wheatley E, et al. Biochem J, 2005 May 15. PMID 15631622, Free PMC Article
  3. Type II myosin heavy chain encoded by the myo2 gene composes the contractile ring during cytokinesis in Schizosaccharomyces pombe. Kitayama C, et al. J Cell Biol, 1997 Jun 16. PMID 9182664, Free PMC Article
  4. Regulation of cell polarity by microtubules in fission yeast. Sawin KE, et al. J Cell Biol, 1998 Jul 27. PMID 9679144, Free PMC Article
  5. Isolation and characterization of Schizosaccharomyces pombe mutants phenotypically similar to ras1-. Fukui Y, et al. Mol Gen Genet, 1988 Dec. PMID 3071741

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables phosphatidylinositol binding ISM
Inferred from Sequence Model
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-macromolecule adaptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein-macromolecule adaptor activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in conjugation with cellular fusion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of mating projection assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of establishment or maintenance of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Cdc42 GTPase complex TAS
Traceable Author Statement
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cortical dynamic polarity patch IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in mating projection tip IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mating projection tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in plasma membrane of cell tip EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
Cdc42 GTPase complex scaffold subunit Scd2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2382504..2385153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019175.3 → NP_593744.1  Cdc42 GTPase complex scaffold subunit Scd2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593744.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P40996
    Conserved Domains (4) summary
    cd06890
    Location:299 → 409
    PX_Bem1p; The phosphoinositide binding Phox Homology domain of Bem1p
    cd11878
    Location:28 → 81
    SH3_Bem1p_1; First Src Homology 3 domain of Bud emergence protein 1 and similar domains
    cd11879
    Location:127 → 182
    SH3_Bem1p_2; Second Src Homology 3 domain of Bud emergence protein 1 and similar domains
    smart00666
    Location:459 → 523
    PB1; PB1 domain
Nucleotide Protein
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