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arc4 ARP2/3 actin-organizing complex subunit Arc4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541767, updated on 18-Sep-2024

Summary

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Official Symbol
arc4
Official Full Name
ARP2/3 actin-organizing complex subunit Arc4
Primary source
PomBase:SPAC6G9.07c
Locus tag
SPOM_SPAC6G9.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
arc19
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Genomic context

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See arc4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (3258471..3259484, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene coenzyme A diphosphatase Neighboring gene gamma tubulin complex linker, pericentrin/kendrin Pcp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin hydrolase Ubp6 Neighboring gene 60S ribosomal protein eL24

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis. Cabrera R, et al. Yeast, 2011 Jun. PMID 21449051, Free PMC Article
  2. A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Morrell JL, et al. Mol Biol Cell, 1999 Dec. PMID 10588653, Free PMC Article
  3. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
  4. Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Chavali SS, et al. Nat Commun, 2024 Mar 6. PMID 38448439, Free PMC Article
  5. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding EXP
Inferred from Experiment
more info
 PubMed 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin filament binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Arp2/3 complex-mediated actin nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in actin cortical patch assembly IC
Inferred by Curator
more info
  
involved_in actin filament branching EXP
Inferred from Experiment
more info
 PubMed 
involved_in endocytosis IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
part_of Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Arp2/3 protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cortical patch IC
Inferred by Curator
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
ARP2/3 actin-organizing complex subunit Arc4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3258471..3259484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019540.3 → NP_594116.1  ARP2/3 actin-organizing complex subunit Arc4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594116.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92352, Q9URL0
    Conserved Domains (1) summary
    pfam05856
    Location:1 → 166
    ARPC4; ARP2/3 complex 20 kDa subunit (ARPC4)
Nucleotide Protein
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