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syt22 guanyl-nucleotide exchange factor [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541783, updated on 18-Sep-2024

Summary

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Official Symbol
syt22
Official Full Name
guanyl-nucleotide exchange factor
Primary source
PomBase:SPAC11E3.11c
Locus tag
SPOM_SPAC11E3.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See syt22 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5302220..5305667, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ER or Golgi multispanning membrane VanZ-like family protein Neighboring gene protein tyrosine phosphatase Pyp3 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene 1,3-beta-glucanosyltransferase Gas5 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast syt22 protein, a putative Arf guanine nucleotide exchange factor, is necessary for new end take off. Fujita A, et al. FEMS Microbiol Lett, 2009 May. PMID 19431238
  2. Arf6 anchors Cdr2 nodes at the cell cortex to control cell size at division. Opalko HE, et al. J Cell Biol, 2022 Feb 7. PMID 34958661, Free PMC Article
  3. A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast. Mitra P, et al. J Cell Biol, 2004 Jul 19. PMID 15249580, Free PMC Article
  4. Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1. Kettenbach AN, et al. Mol Cell Proteomics, 2015 May. PMID 25720772, Free PMC Article
  5. Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome. Telekawa C, et al. Nucleic Acids Res, 2018 Nov 30. PMID 30321377, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell growth mode switching, monopolar to bipolar IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport ISM
Inferred from Sequence Model
more info
  
involved_in positive regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signaling IC
Inferred by Curator
more info
  
involved_in vesicle-mediated transport ISM
Inferred from Sequence Model
more info
  
Component Evidence Code Pubs
is_active_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell cortex of cell tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
guanyl-nucleotide exchange factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5302220..5305667 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020367.3 → NP_594936.1  guanyl-nucleotide exchange factor [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594936.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13690
    Conserved Domains (3) summary
    smart00222
    Location:296 → 499
    Sec7; Sec7 domain
    COG5307
    Location:1 → 942
    COG5307; Guanine-nucleotide exchange factor, contains Sec7 domain [General function prediction only]
    pfam15410
    Location:679 → 804
    PH_9; Pleckstrin homology domain
Nucleotide Protein
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