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rrp4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541813, updated on 11-Sep-2024

Summary

Official Symbol
rrp4
Primary source
PomBase:SPAC2F7.14c
Locus tag
SPOM_SPAC2F7.14C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (560824..562161, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RNA-binding protein Nrd1 Neighboring gene tryptophan-tRNA ligase Wrs1 Neighboring gene ncRNA Neighboring gene ncRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in CUT catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in TRAMP-dependent tRNA surveillance pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in U4 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nonfunctional rRNA decay ISO
Inferred from Sequence Orthology
more info
 
involved_in nuclear mRNA surveillance TAS
Traceable Author Statement
more info
PubMed 
involved_in nuclear polyadenylation-dependent mRNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in nuclear polyadenylation-dependent rRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nuclear-transcribed mRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay ISO
Inferred from Sequence Orthology
more info
 
involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nuclear-transcribed mRNA catabolic process, non-stop decay ISO
Inferred from Sequence Orthology
more info
 
involved_in poly(A)-dependent snoRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of chromatin IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytoplasmic exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol HDA PubMed 
part_of exosome (RNase complex) IDA
Inferred from Direct Assay
more info
PubMed 
part_of nuclear exosome (RNase complex) EXP
Inferred from Experiment
more info
PubMed 
part_of nuclear exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus HDA PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    560824..562161 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018384.3NP_592984.1  exosome subunit Rrp4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592984.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09704
    Conserved Domains (4) summary
    COG1097
    Location:48295
    Rrp4; Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains [Translation, ribosomal structure and biogenesis]
    cd05789
    Location:106197
    S1_Rrp4; S1_Rrp4: Rrp4 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Rrp4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation in ...
    pfam14382
    Location:5794
    ECR1_N; Exosome complex exonuclease RRP4 N-terminal region
    pfam15985
    Location:200240
    KH_6; KH domain