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ubp6 ubiquitin hydrolase Ubp6 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541819, updated on 18-Sep-2024

Summary

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Official Symbol
ubp6
Official Full Name
ubiquitin hydrolase Ubp6
Primary source
PomBase:SPAC6G9.08
Locus tag
SPOM_SPAC6G9.08
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ubp6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3259605..3262222)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene gamma tubulin complex linker, pericentrin/kendrin Pcp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ARP2/3 actin-organizing complex subunit Arc4 Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL24 Neighboring gene helicase Sen1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast. Stone M, et al. J Mol Biol, 2004 Nov 26. PMID 15533439
  2. Widespread cotranslational formation of protein complexes. Duncan CD, et al. PLoS Genet, 2011 Dec. PMID 22144913, Free PMC Article
  3. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. Kouranti I, et al. PLoS Biol, 2010 Sep 7. PMID 20838651, Free PMC Article
  4. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article
  5. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal-dependent deubiquitinase activity HDA PubMed 
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
NOT is_active_in nucleolus HDA PubMed 
is_active_in nucleoplasm HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
ubiquitin hydrolase Ubp6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3259605..3262222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019541.3 → NP_594117.2  ubiquitin hydrolase Ubp6 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594117.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q92353
    Conserved Domains (4) summary
    smart00213
    Location:3 → 73
    UBQ; Ubiquitin homologues
    cd02657
    Location:102 → 463
    Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...
    pfam00240
    Location:10 → 72
    ubiquitin; Ubiquitin family
    pfam00443
    Location:100 → 462
    UCH; Ubiquitin carboxyl-terminal hydrolase
Nucleotide Protein
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