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npr2 Npr2/3 complex subunit Npr2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541840, updated on 18-Sep-2024

Summary

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Official Symbol
npr2
Official Full Name
Npr2/3 complex subunit Npr2
Primary source
PomBase:SPAC23H3.03c
Locus tag
SPOM_SPAC23H3.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See npr2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2495844..2497562, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RING finger-like protein Ini1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TORC1 signaling is governed by two negative regulators in fission yeast. Ma N, et al. Genetics, 2013 Oct. PMID 23934889, Free PMC Article
  2. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast. Ma N, et al. PLoS One, 2016. PMID 27227887, Free PMC Article
  3. Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase. Fukuda T, et al. Elife, 2021 Feb 3. PMID 33534698, Free PMC Article
  4. Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases. Chia KH, et al. Elife, 2017 Dec 4. PMID 29199950, Free PMC Article
  5. TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose. Toyoda Y, et al. J Cell Sci, 2021 May 15. PMID 34028542

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTPase activator activity EXP
Inferred from Experiment
more info
 PubMed 
contributes_to GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to GTPase activator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of TORC1 signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of GATOR1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GATOR1 complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
part_of GATOR1 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in vacuolar membrane EXP
Inferred from Experiment
more info
 PubMed 
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Npr2/3 complex subunit Npr2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2495844..2497562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019222.3 → NP_593793.1  Npr2/3 complex subunit Npr2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593793.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42857
    Conserved Domains (1) summary
    cl24021
    Location:19 → 402
    NPR3; Nitrogen Permease regulator of amino acid transport activity 3
Nucleotide Protein
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