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hpt1 xanthine phosphoribosyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541970, updated on 22-Jun-2024

Summary

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Gene symbol
hpt1
Gene description
xanthine phosphoribosyltransferase
Locus tag
SPOM_SPAC23C11.13C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pur1
Old locus tag
SPAC23C11.13c
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Genomic context

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See hpt1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2155374..2156517, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase Cka1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe accessory factor subunit Hcn1/Apc12 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The substrate specificity of purine phosphoribosyltransferases in Schizosaccharomyces pombe. De Groodt A, et al. Biochem J, 1971 May. PMID 5123876, Free PMC Article
  2. Purification and comparative study of adenine and guanine phosphoribosyltransferases from Schizosaccharomyces pombe. Nagy M, et al. Eur J Biochem, 1977 Jul 1. PMID 20306
  3. Study of the role of puring phosphoribosyltransferases in the uptake of adenine and guanine by Schizosaccharomyces pombe cells. Housset P, et al. Eur J Biochem, 1977 Feb 15. PMID 14008
  4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables guanine phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hypoxanthine phosphoribosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hypoxanthine phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pentosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables xanthine phosphoribosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in GMP salvage EXP
Inferred from Experiment
more info
 PubMed 
involved_in GMP salvage IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in GMP salvage IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in IMP salvage EXP
Inferred from Experiment
more info
 PubMed 
involved_in IMP salvage IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in XMP salvage IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in hypoxanthine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in purine ribonucleoside salvage IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
xanthine phosphoribosyltransferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2155374..2156517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019075.3 → NP_593644.1  xanthine phosphoribosyltransferase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593644.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13917
    Conserved Domains (1) summary
    COG2236
    Location:2 → 197
    Hpt1; Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]
Nucleotide Protein
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