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hem1 5-aminolevulinate synthase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542028, updated on 18-Sep-2024

Summary

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Official Symbol
hem1
Official Full Name
5-aminolevulinate synthase
Primary source
PomBase:SPAC2F3.09
Locus tag
SPOM_SPAC2F3.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See hem1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3939665..3942086)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribonuclease kappa-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GARP complex subunit Vps54

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Shu1 is a cell-surface protein involved in iron acquisition from heme in Schizosaccharomyces pombe. Mourer T, et al. J Biol Chem, 2015 Apr 17. PMID 25733668, Free PMC Article
  2. The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring. Roberts-Galbraith RH, et al. J Cell Biol, 2009 Jan 12. PMID 19139265, Free PMC Article
  3. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
  4. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article
  5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 5-aminolevulinate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 5-aminolevulinate synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in heme biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in heme biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protoporphyrinogen IX biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
5-aminolevulinate synthase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3939665..3942086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019809.3 → NP_594388.1  5-aminolevulinate synthase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594388.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14092
    Conserved Domains (3) summary
    COG0156
    Location:132 → 525
    BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
    PRK09064
    Location:133 → 532
    PRK09064; 5-aminolevulinate synthase; Validated
    pfam09029
    Location:11 → 53
    Preseq_ALAS; 5-aminolevulinate synthase presequence
Nucleotide Protein
Heading Accession and Version

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