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mpn1 3'-5'-RNA exonuclease Mpn1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542061, updated on 18-Sep-2024

Summary

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Official Symbol
mpn1
Official Full Name
3'-5'-RNA exonuclease Mpn1
Primary source
PomBase:SPAC23C11.10
Locus tag
SPOM_SPAC23C11.10
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
usb1
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Genomic context

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See mpn1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (2150624..2151601)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene alanine--tRNA (Ala) ligase Ala1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Cka1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human Mpn1 promotes post-transcriptional processing and stability of U6atac. Shchepachev V, et al. FEBS Lett, 2015 Aug 19. PMID 26213367
  2. Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA. Shchepachev V, et al. Cell Rep, 2012 Oct 25. PMID 23022480
  3. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
  4. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
  5. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in U6 snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in U6 snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
3'-5'-RNA exonuclease Mpn1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2150624..2151601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019072.1 → NP_593641.2  3'-5'-RNA exonuclease Mpn1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593641.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13915
    Conserved Domains (1) summary
    pfam09749
    Location:29 → 262
    HVSL; uncharacterized conserved protein
Nucleotide Protein
Heading Accession and Version

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