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lys1 aminoadipate-semialdehyde dehydrogenase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542079, updated on 18-Sep-2024

Summary

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Official Symbol
lys1
Official Full Name
aminoadipate-semialdehyde dehydrogenase
Primary source
PomBase:SPAP7G5.04c
Locus tag
SPOM_SPAP7G5.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lys1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3739076..3743449, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene conjugation protein Prm1 Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L10 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular properties of the lys1+ gene and the regulation of alpha-aminoadipate reductase in Schizosaccharomyces pombe. Ford RA, et al. Curr Genet, 1995 Jul. PMID 8590464
  2. Physical and functional characterization of the cloned lys1+ gene of Schizosaccharomyces pombe. Ford RA, et al. J Basic Microbiol, 1993. PMID 8350245
  3. Cloning the Schizosaccharomyces pombe lys2+ gene and construction of new molecular genetic tools. Hoffman RL, et al. Curr Genet, 2006 Jun. PMID 16491385, Free PMC Article
  4. Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes alpha-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) from Schizosaccharomyces pombe. Guo S, et al. Yeast, 2004 Nov. PMID 15546125
  5. Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe. Ye ZH, et al. J Bacteriol, 1988 Dec. PMID 3142867, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables L-aminoadipate-semialdehyde dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-aminoadipate-semialdehyde dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables phosphopantetheine binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lysine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in lysine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in lysine biosynthetic process via aminoadipic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
aminoadipate-semialdehyde dehydrogenase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3739076..3743449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019737.3 → NP_594314.1  aminoadipate-semialdehyde dehydrogenase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594314.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P40976, Q9P770
    Conserved Domains (5) summary
    cd05235
    Location:1006 → 1303
    SDR_e1; extended (e) SDRs, subgroup 1
    cd05930
    Location:311 → 858
    A_NRPS; The adenylation domain of nonribosomal peptide synthetases (NRPS)
    TIGR03443
    Location:17 → 1417
    alpha_am_amid; L-aminoadipate-semialdehyde dehydrogenase
    pfam00550
    Location:887 → 952
    PP-binding; Phosphopantetheine attachment site
    cl23853
    Location:18 → 100
    Condensation; Condensation domain
Nucleotide Protein
Heading Accession and Version

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