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lys7 alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542118, updated on 18-Sep-2024

Summary

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Official Symbol
lys7
Official Full Name
alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7
Primary source
PomBase:SPAC17C9.02c
Locus tag
SPOM_SPAC17C9.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See lys7 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (4496725..4498140)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene mediator complex subunit Med27 Neighboring gene translation initiation factor eIF4G Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene anaphase-promoting complex TPR lobe subcomplex subunit Apc3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Posttranslational activation, site-directed mutation and phylogenetic analyses of the lysine biosynthesis enzymes alpha-aminoadipate reductase Lys1p (AAR) and the phosphopantetheinyl transferase Lys7p (PPTase) from Schizosaccharomyces pombe. Guo S, et al. Yeast, 2004 Nov. PMID 15546125
  2. Functional characterization of 4'-phosphopantetheinyl transferase genes of bacterial and fungal origin by complementation of Saccharomyces cerevisiae lys5. Mootz HD, et al. FEMS Microbiol Lett, 2002 Jul 16. PMID 12127488
  3. Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe. Ye ZH, et al. J Bacteriol, 1988 Dec. PMID 3142867, Free PMC Article
  4. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables holo-[acyl-carrier-protein] synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables holo-[acyl-carrier-protein] synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lysine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in lysine biosynthetic process via aminoadipic acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lysine biosynthetic process via aminoadipic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4496725..4498140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020031.3 → NP_594603.1  alpha-aminoadipate reductase phosphopantetheinyl transferase Lys7 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594603.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10474
    Conserved Domains (2) summary
    COG2091
    Location:3 → 243
    Sfp; Phosphopantetheinyl transferase [Coenzyme transport and metabolism]
    cl00500
    Location:122 → 214
    ACPS; 4'-phosphopantetheinyl transferase superfamily
Nucleotide Protein
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