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upf2 nonsense-mediated decay protein Upf2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542147, updated on 18-Sep-2024

Summary

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Official Symbol
upf2
Official Full Name
nonsense-mediated decay protein Upf2
Primary source
PomBase:SPAC19A8.08
Locus tag
SPOM_SPAC19A8.08
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See upf2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (2468576..2472061, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene recombination protein Irc6 Neighboring gene SUMO-targeted ubiquitin-protein ligase subunit Rfp1 Neighboring gene ncRNA Neighboring gene transport protein Yos1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein prl65

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. Mendell JT, et al. Mol Cell Biol, 2000 Dec. PMID 11073994, Free PMC Article
  2. Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex. Hayashi T, et al. Genes Cells, 2014 Jul. PMID 24774534
  3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay ISO
Inferred from Sequence Orthology
more info
  
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of mRNA stability involved in response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
part_of exon-exon junction complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nonsense-mediated decay protein Upf2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2468576..2472061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019213.2 → NP_593784.1  nonsense-mediated decay protein Upf2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593784.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13824
    Conserved Domains (4) summary
    smart00543
    Location:447 → 634
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam02854
    Location:649 → 855
    MIF4G; MIF4G domain
    pfam04050
    Location:901 → 1047
    Upf2; Up-frameshift suppressor 2
    cl02652
    Location:41 → 281
    MIF4G; MIF4G domain
Nucleotide Protein
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