U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cdc16 two-component GAP Cdc16 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542162, updated on 22-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
cdc16
Gene description
two-component GAP Cdc16
Locus tag
SPOM_SPAC6F6.08C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
bub2
Old locus tag
SPAC6F6.08c
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cdc16 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (2746667..2748156, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene cell polarity factor Rax2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS15 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NuA4 histone acetyltransferase complex subunit Eaf6

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe. Minet M, et al. J Bacteriol, 1979 Jan. PMID 762020, Free PMC Article
  2. Dynamics of SIN asymmetry establishment. Bajpai A, et al. PLoS Comput Biol, 2013. PMID 23874188, Free PMC Article
  3. The role of Plo1 kinase in mitotic commitment and septation in Schizosaccharomyces pombe. Tanaka K, et al. EMBO J, 2001 Mar 15. PMID 11250892, Free PMC Article
  4. Regions of Byr4, a regulator of septation in fission yeast, that bind Spg1 or Cdc16 and form a two-component GTPase-activating protein with Cdc16. Furge KA, et al. J Biol Chem, 1999 Apr 16. PMID 10196225
  5. The fission yeast dma1 gene is a component of the spindle assembly checkpoint, required to prevent septum formation and premature exit from mitosis if spindle function is compromised. Murone M, et al. EMBO J, 1996 Dec 2. PMID 8978687, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Tea4-PP1 landmark promotes local Cdc42 activation and growth both through Cdc42 GEF recruitment and by creating a local trough in a Cdc42 GAP.
    Title: The Tea4-PP1 landmark promotes local growth by dual Cdc42 GEF recruitment and GAP exclusion.
  2. We propose a mechanism that limits the amount of the Byr4p-Cdc16p GAP to the amount required to inhibit Spg1p signalling.
    Title: Homoeostasis between the GTPase Spg1p and its GAP in the regulation of cytokinesis in S. pombe.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
contributes_to GTPase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of division septum assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of septation initiation signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of Bfa1-Bub2 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in mitotic spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in old mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
two-component GAP Cdc16

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2746667..2748156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019331.3 → NP_593901.1  two-component GAP Cdc16 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593901.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P36618
    Conserved Domains (2) summary
    smart00164
    Location:38 → 244
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    COG5210
    Location:1 → 299
    COG5210; GTPase-activating protein [General function prediction only]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials