U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gcn1 translation initiation regulator Gcn1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542235, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
gcn1
Official Full Name
translation initiation regulator Gcn1
Primary source
PomBase:SPAC18G6.05c
Locus tag
SPOM_SPAC18G6.05C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gcn1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2219135..2227390, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Rab11 family GTPase Ypt3 Neighboring gene ncRNA Neighboring gene serine hydroxymethyltransferase Shm2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Activation of Gcn2 in response to different stresses. Anda S, et al. PLoS One, 2017. PMID 28771613, Free PMC Article
  2. Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase. Fukuda T, et al. Elife, 2021 Feb 3. PMID 33534698, Free PMC Article
  3. Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor. Hanyu Y, et al. Genes Cells, 2009 May. PMID 19371376
  4. Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Roberts-Galbraith RH, et al. Mol Cell, 2010 Jul 9. PMID 20603077, Free PMC Article
  5. Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast. Hirano Y, et al. J Biochem, 2023 Jun 30. PMID 36799444

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein kinase activator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosome binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic G1 DNA damage checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of cytoplasmic translational initiation IDA
Inferred from Direct Assay
more info
 PubMed 
NOT involved_in positive regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
translation initiation regulator Gcn1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2219135..2227390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019101.3 → NP_593669.1  translation initiation regulator Gcn1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593669.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10105
    Conserved Domains (5) summary
    COG1413
    Location:1646 → 1843
    HEAT; HEAT repeat [General function prediction only]
    pfam12074
    Location:376 → 723
    DUF3554; Domain of unknown function (DUF3554)
    pfam13513
    Location:1616 → 1668
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:1946 → 2047
    HEAT_2; HEAT repeats
    sd00044
    Location:1642 → 1670
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials