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arc2 ARP2/3 actin-organizing complex subunit Arc34 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542287, updated on 18-Sep-2024

Summary

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Official Symbol
arc2
Official Full Name
ARP2/3 actin-organizing complex subunit Arc34
Primary source
PomBase:SPAC6F6.10c
Locus tag
SPOM_SPAC6F6.10C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
arc34
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Genomic context

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See arc2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2749724..2750982, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene NuA4 histone acetyltransferase complex subunit Eaf6 Neighboring gene ncRNA Neighboring gene pyridoxine-pyridoxal-pyridoxamine kinase Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Chavali SS, et al. Nat Commun, 2024 Mar 6. PMID 38448439, Free PMC Article
  2. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
  3. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article
  4. Pathway of actin filament branch formation by Arp2/3 complex. Beltzner CC, et al. J Biol Chem, 2008 Mar 14. PMID 18165685
  5. GMF is an evolutionarily developed Adf/cofilin-super family protein involved in the Arp2/3 complex-mediated organization of the actin cytoskeleton. Nakano K, et al. Cytoskeleton (Hoboken), 2010 Jun. PMID 20517925

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables actin filament binding EXP
Inferred from Experiment
more info
 PubMed 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin filament binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Arp2/3 complex-mediated actin nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in actin cortical patch assembly IC
Inferred by Curator
more info
  
involved_in actin filament branching EXP
Inferred from Experiment
more info
 PubMed 
involved_in endocytosis IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
part_of Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Arp2/3 protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin cortical patch IC
Inferred by Curator
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cell tip HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
ARP2/3 actin-organizing complex subunit Arc34

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2749724..2750982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019333.3 → NP_593903.1  ARP2/3 actin-organizing complex subunit Arc34 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593903.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14241
    Conserved Domains (1) summary
    pfam04045
    Location:52 → 302
    P34-Arc; Arp2/3 complex, 34 kD subunit p34-Arc
Nucleotide Protein
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