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ssl3 cohesin loading factor Ssl3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542301, updated on 18-Sep-2024

Summary

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Official Symbol
ssl3
Official Full Name
cohesin loading factor Ssl3
Primary source
PomBase:SPAC1687.18c
Locus tag
SPOM_SPAC1687.18C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ssl3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (936188..938118, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Der1 family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene queuine tRNA-ribosyltransferase Neighboring gene centromere connector protein mis6 Neighboring gene fructose-2,6-bisphosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cell-cycle regulation of cohesin stability along fission yeast chromosomes. Bernard P, et al. EMBO J, 2008 Jan 9. PMID 18079700, Free PMC Article
  2. Conserved roles of chromatin remodellers in cohesin loading onto chromatin. Muñoz S, et al. Curr Genet, 2020 Oct. PMID 32277274, Free PMC Article
  3. A Brownian ratchet model for DNA loop extrusion by the cohesin complex. Higashi TL, et al. Elife, 2021 Jul 26. PMID 34309513, Free PMC Article
  4. Biochemical reconstitution of topological DNA binding by the cohesin ring. Murayama Y, et al. Nature, 2014 Jan 16. PMID 24291789, Free PMC Article
  5. Establishment of DNA-DNA Interactions by the Cohesin Ring. Murayama Y, et al. Cell, 2018 Jan 25. PMID 29358048, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables cohesin loader activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin looping IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in maintenance of mitotic sister chromatid cohesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic sister chromatid cohesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitotic sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SMC loading complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SMC loading complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Scc2-Scc4 cohesin loading complex EXP
Inferred from Experiment
more info
 PubMed 
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
cohesin loading factor Ssl3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    936188..938118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018533.3 → NP_593137.1  cohesin loading factor Ssl3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593137.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94459
    Conserved Domains (1) summary
    pfam10345
    Location:14 → 550
    Cohesin_load; Cohesin loading factor
Nucleotide Protein
Heading Accession and Version

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