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srb6 mediator complex subunit Med22 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542413, updated on 18-Sep-2024

Summary

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Official Symbol
srb6
Official Full Name
mediator complex subunit Med22
Primary source
PomBase:SPAC29A4.07
Locus tag
SPOM_SPAC29A4.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
med22
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Genomic context

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See srb6 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5133784..5136019, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA exonuclease Rrp17 Neighboring gene ncRNA Neighboring gene Prp19 complex subunit, ubiquitin-protein ligase E4 Prp19 Neighboring gene splicing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene myosin I light chain Cam2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the Mediator head module. Larivière L, et al. Nature, 2012 Dec 20. PMID 23123849
  2. Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system. Tamayo E, et al. Eur J Biochem, 2004 Jun. PMID 15182371
  3. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
  4. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription coactivator activity EXP
Inferred from Experiment
more info
 PubMed 
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription initiation by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mediator complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mediator complex subunit Med22

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5133784..5136019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020304.3 → NP_594875.1  mediator complex subunit Med22 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594875.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14010
    Conserved Domains (1) summary
    pfam06179
    Location:21 → 116
    Med22; Surfeit locus protein 5 subunit 22 of Mediator complex
Nucleotide Protein
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