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kap95 karyopherin/importin beta family nuclear import signal receptor Kap95 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542496, updated on 18-Sep-2024

Summary

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Official Symbol
kap95
Official Full Name
karyopherin/importin beta family nuclear import signal receptor Kap95
Primary source
PomBase:SPAC1B1.03c
Locus tag
SPOM_SPAC1B1.03C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See kap95 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3541416..3544293, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor Deb1/Rdp1 Neighboring gene NAD/NADH kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene poly(A)-specific ribonuclease complex subunit Pan3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple conserved domains of the nucleoporin Nup124p and its orthologs Nup1p and Nup153 are critical for nuclear import and activity of the fission yeast Tf1 retrotransposon. Sistla S, et al. Mol Biol Cell, 2007 Sep. PMID 17615301, Free PMC Article
  2. Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis. Chen XQ, et al. Yeast, 2004 Apr 30. PMID 15116432
  3. Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast. Hirano Y, et al. J Biochem, 2023 Jun 30. PMID 36799444
  4. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article
  5. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding NAS
Non-traceable Author Statement
more info
  
enables nuclear import signal receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle midzone IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nuclear envelope HDA PubMed 
is_active_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore NAS
Non-traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
karyopherin/importin beta family nuclear import signal receptor Kap95

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3541416..3544293 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019656.3 → NP_594233.1  karyopherin/importin beta family nuclear import signal receptor Kap95 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594233.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13864
    Conserved Domains (5) summary
    COG5215
    Location:1 → 863
    KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]
    cd00020
    Location:409 → 480
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam03810
    Location:21 → 101
    IBN_N; Importin-beta N-terminal domain
    pfam13513
    Location:380 → 435
    HEAT_EZ; HEAT-like repeat
    sd00044
    Location:323 → 354
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
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