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med1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542516, updated on 11-Sep-2024

Summary

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Official Symbol
med1
Primary source
PomBase:SPAC2F7.04
Locus tag
SPOM_SPAC2F7.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pmc2
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Genomic context

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Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (537910..540012)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DYRK family cell polarity protein kinase Pom1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation initiation factor Tif5 Neighboring gene DNA polymerase X family Neighboring gene ncRNA Neighboring gene Clr6 histone deacetylase-associated PHD protein-2 Cph2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions. Reddy BD, et al. Genes Dev, 2011 Feb 1. PMID 21289066, Free PMC Article
  2. TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes. Cohen A, et al. PLoS Genet, 2022 Feb. PMID 35157728, Free PMC Article
  3. Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways. Linder T, et al. Nucleic Acids Res, 2008 May. PMID 18310102, Free PMC Article
  4. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
  5. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription initiation by RNA polymerase II EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of mediator complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
mediator complex subunit Med1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    537910..540012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018375.3 → NP_592975.1  mediator complex subunit Med1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592975.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09696
    Conserved Domains (1) summary
    pfam10744
    Location:40 → 357
    Med1; Mediator of RNA polymerase II transcription subunit 1
Nucleotide Protein
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